Eastern South Dakota Vacation Packages 2026 from $396

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Your Eastern South Dakota Vacation

Locking in one of our vacation packages to Eastern South Dakota makes it a breeze to see and do more. Get set to experience this exciting destination's rural countryside and beyond. Your trip to Eastern South Dakota wouldn't be complete without getting to some of its best cities, starting with Sioux Falls. Some of the most popular attractions here include Denny Sanford Premier Center and Empire Mall. Mitchell is another favorite with Eastern South Dakota travelers. Visitors to this exciting destination enjoy Corn Palace and Mitchell Aquatic Center. Start packing your bags, because your Eastern South Dakota vacation is just a few clicks away with Expedia.

The Latest Eastern South Dakota vacation packages

Price found within the past 48 hours. Click for updated prices.

Super 8 by Wyndham Mitchell

$396

per person

Jan 6 - Jan 12

found 3 hours ago

Roundtrip flight included

Minneapolis (MSP) to Sioux Falls (FSD)

6.8/10 (1,014 reviews)

The stains in the room were really bad. I left my socks on all night. No way would I sit on the couch. The bed and bathroom were clean. Mattress was comfortable. Pillows were terrible. Staff friendly. Breakfast was a basic and as minimally stocked as they could get away with. Fine for 1 night for the price.

Reviewed on Oct 13, 2026

Super 8 by Wyndham Watertown

$408

per person

Jan 6 - Jan 12

found 3 hours ago

Roundtrip flight included

Minneapolis (MSP) to Watertown (ATY)

6.6/10 (776 reviews)

Grandstay Hotel and Suites Milbank

$619

per person

Jan 6 - Jan 12

found 3 hours ago

Roundtrip flight included

Minneapolis (MSP) to Watertown (ATY)

9.4/10 Exceptional! (310 reviews)

Super 8 by Wyndham Madison

$433

per person

Jan 6 - Jan 12

found 3 hours ago

Roundtrip flight included

Minneapolis (MSP) to Sioux Falls (FSD)

6.4/10 (285 reviews)

Days Inn by Wyndham North Sioux City

$408

per person

Jan 6 - Jan 12

found 3 hours ago

Roundtrip flight included

Minneapolis (MSP) to Sioux Falls (FSD)

6.8/10 (648 reviews)

Very friendly and helpful staff

Reviewed on Oct 13, 2026

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Where to stay in Eastern South Dakota

Find the best Eastern South Dakota areas and neighborhoods for the activities you enjoy most. Learn more about Eastern South Dakota

Downtown Sioux Falls

1 out of top 10 points of interest in this area

While visiting Downtown Sioux Falls, you might make a stop by sights like Washington Pavilion of Arts and Science and Old Courthouse Museum.

A waterfall, a stone building, and modern buildings at dusk.

Mall District

1 out of top 10 points of interest in this area

While visiting Mall District, you might make a stop by sights like Empire Mall and The District.

A river flowing through a rocky landscape with trees and ancient ruins.

Northwest Sioux Falls

2 out of top 10 points of interest in this area

While visiting Northwest Sioux Falls, you might make a stop by sights like Sanford Pentagon and Sioux Falls Arena.

A waterfall cascading over rocks into a pool, surrounded by a rocky landscape with sparse vegetation.

University Heights

1 out of top 10 points of interest in this area

If you're spending some time in University Heights, Edith Mortenson Theatre Center and Center for Western Studies are top sights worth seeing.

A waterfall cascading over rocky terrain with a wooden structure in the background.

South Sioux Falls

If you're looking for some top things to see and do in South Sioux Falls and surrounding area, you can visit Empire Mall and The District.

Stay near popular Eastern South Dakota attractions

A waterfall cascading over rocky terrain with a bridge in the background.

Falls Park

9.4/10 (2,165 reviews)

Falls Park is just one of the places to see in Sioux Falls, so why not enjoy the other things to explore during your travels? Attend a sporting event or discover the area's beautiful waterfalls.

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An aerial view of a university campus with multiple buildings, parking lots, and green spaces.

South Dakota State University

9.6/10 (334 reviews)

Enjoy the collegiate vibe when you visit South Dakota State University, during your trip to Brookings. Experience the area's museums and live music.

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A vintage theremin with a label, a grand piano, and a decorative panel.

University of South Dakota

9.2/10 (114 reviews)

Explore the campus of University of South Dakota, during your trip to Vermillion. While in this family-friendly area, you can savor the bars and restaurants.

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Denny Sanford Premier Center

8.8/10 (879 reviews)

You can take time to visit Denny Sanford Premier Center during your travels to Sioux Falls. Attend a sporting event or discover the area's beautiful waterfalls.

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Empire Mall

8.6/10 (1,567 reviews)

You can enjoy retail therapy at Empire Mall during your stay in Sioux Falls. Attend a sporting event or discover the area's beautiful waterfalls.

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Sanford Pentagon

8.2/10 (320 reviews)

Catch an event at Sanford Pentagon during your trip to Sioux Falls. Attend a sporting event or discover the area's beautiful waterfalls.

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Sioux Falls Convention Center

8.4/10 (298 reviews)

Learn about the events happening at Sioux Falls Convention Center during your trip to Sioux Falls. Attend a sporting event or discover the area's beautiful waterfalls.

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Augustana College

8.2/10 (310 reviews)

Take a campus tour or just explore the area of Augustana College, during your trip to Sioux Falls. Attend a sporting event or discover the area's beautiful waterfalls.

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Eastern South Dakota Hotel Deals

Ramada by Wyndham Sioux Falls Airport-Waterpark & Event Ctr

1301 West Russell Sioux Falls SD

Fully refundableReserve now, pay when you stay

$62 nightly

$70 total

Nov 1 - Nov 2

Total with taxes and fees

7.8/10 Good! (1,662 reviews)

"Kids screaming bloody murder looking for his mom and at 5:30 there was domestic violence and woke me up"

Reviewed on Oct 14, 2026

Hotel On Phillips

100 N Phillips Ave Sioux Falls SD

Fully refundableReserve now, pay when you stay

$209 nightly

$231 total

Oct 18 - Oct 19

Total with taxes and fees

Days Inn by Wyndham Sioux Falls Empire

3401 Gateway Blvd Sioux Falls SD

Fully refundableReserve now, pay when you stay

$61 nightly

$69 total

Oct 19 - Oct 20

Total with taxes and fees

See all 1,011 properties in Eastern South Dakota

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.